 The  is an advanced proprietary filter specifically designed for
use in hemodiafiltration therapy. It uniquely combines post - dilution and
pre - dilution diafiltration into one elegant and simple - to - use filter design. As a
result, the achieves the superior urea clearance of post - dilution
hemodiafiltration, while offering unsurpassed clearance of toxins in the middle-
molecule range.
The construction of the is similar to a typical hollow fiber
dialyzer, using a s ingle fiberbundle. A ring - shaped groove in the potting
compound at one end and a two compartment header cap are used to
separate the fiber bundle into two discrete but serially connected blood paths:
an oute fluid inlet port is provided on the opposite header to deliver s ubstitution
fluid in mid-stage dilution mode.
  1Locatelli,,et. al., Comparison of mortality in ESRD patients on convective and
diffusive extracorporeal treatments; Kidney Intl 1999; 55: 286-293
2Held, et. al., The dose of Hemodialysis and Patient Mortality, Kidney
International 1996; 50: 550-556
3Leypolt, et. al., Effect of Dialysis Membranes and Middle Molecule
Removal on Chronic Hemodialysis Patient Survival, Amer. Journal of
Kidney Diseases 1999; 33: 349-355
4Canaud, et. al., Ultrafiltration and Convective - Based Dialysis Modalities:
New Trends and Applications for Renal Replacement Therapy in ESRD
Patients, Nephrol Dial Transplant 1999; 14(Suppl 3): 98-105
5Canaud, et. al., Hemodiafiltration with On - Line Production of Bicarbonate
Infusate; in Baldemus et. al. (eds), Improvements in Dialysis Therapy,
Contrib Nephrol; Basel, Karger 1989; 74: 91-100
6Maduell,,et. al., Change from conventional haemodiafiltration t on - line
haemodiafiltration, Nephrol Dial Transplant 1999; 14: 1202-1207
7Minutolo, et. al., Postdialytic Rebound of Serum Phosphorus: Pathogenetic
and Clinical Insights; J Am Soc Nephrol 2002; 13: 1046-1054.
This product is currently approved for sale in the European Union.
This product is not yet FDA approved for sale in the US.
|
